What is Orencia®?

Orencia® (abatacept) is a protein that stops the immune system from attacking healthy tissues like joints. The immune system aids in the fight against infections in the body. In persons with autoimmune illnesses, the immune system misidentifies and attacks the body's own cells as intruders. Orencia® is a Prescription Medication used to treat the symptoms of rheumatoid arthritis and to prevent joint deterioration. This drug is only for adults and children over the age of two. Orencia® is also used to treat adults with active psoriatic arthritis. Orencia® isn't a cure for autoimmune disorders; it just treats the symptoms.

What Orencia® is Used For?

Orencia® contains abatacept; a medicine which is used to treat:

  • Moderate to severe rheumatoid arthritis in adults.
  • Severe, active, and progressive rheumatoid arthritis.
  • Psoriatic arthritis in adults.
  • Polyarticular juvenile idiopathic arthritis.

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How Orencia® is Given?

Your healthcare practitioner will tell you how to inject Orencia®. A different site should be used for each new injection. Each new injection site should be approximately 1 inch (2.5cm) from where you last injected Orencia®. The recommended dose is 125mg per week regardless of your weight and Orencia® should be injected under the skin. The Subcutaneous Injection can be given with or without an intravenous loading dose. Your doctor will determine whether you will receive an intravenous loading dose prior to using your solution for injection.

Who Should Not Take Orencia®?

Do not use abatacept if you are allergic to abatacept or any ingredients of the medication have or are at risk of Sepsis Syndromes (an infection that spreads through your body), such as people with weakened immune systems and people with HIV.

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Side Effects of Orencia®:

Common side effects include but are not limited to:

  • Headache
  • Nausea
  • Diarrhea
  • Stomach Pain
  • Indigestion
  • Dizziness
  • Flushing
  • Back Pain
  • Cold Symptoms Such As Stuffy Head/Nose, Sneezing, Sore Throat, Or Cough
  • Fever
  • Chills
  • Night Sweats
  • Flu Symptoms
  • Weight Loss
  • Feeling Very Tired
  • Fatal Infections
  • Shortness Of Breath
  • Changes In The Amount Of Urine
  • Pain When Urinating
  • Severe Abdominal Pain

Cautions To Take Orencia®:

You should not use Orencia® if you are allergic to abatacept.
Before using Orencia®, tell your doctor if you have ever had tuberculosis.
Tell your doctor if you are pregnant or breastfeeding.
To make sure Orencia® is safe for you, tell your doctor if you have ever had:

  • A Weak Immune System
  • Any Type Of Infection Including A Skin Infection Or Open Sores
  • Infections That Go Away And Come Back
  • Copd (Chronic Obstructive Pulmonary Disease)
  • Diabetes
  • Hepatitis 
  • If You Are Scheduled To Receive Any Vaccines

Frequently Asked Questions

1. What should I avoid while taking Orencia®?

Orencia® and other medicines may affect each other, which could cause serious side effects. You should avoid taking Orencia® with other biologics that may affect your immune system. Tell your doctor if you are taking other medicines. It is a good idea to keep an up-to-date list of all of your medicines, vitamins, and herbal supplements on hand to show your doctors.

2. How will I receive Orencia®?

Orencia® is available in two forms, as intravenous (IV) infusions and as subcutaneous (SC) injections. Orencia® infusion is given by a healthcare provider through a vein in your arm.

3. What if prefilled syringe appears to be broken or damaged?

Do not use the prefilled syringe. Contact your healthcare provider for further instructions.

4. Is it a normal to feel a little bit of burning or pain during injection?

You may feel a prick from the needle. Sometimes, the medicine can cause slight irritation near the injection site. Discomfort should be mild to moderate. If you have any side effects, including pain, swelling, or discoloration near the injection site, contact your healthcare provider.

5. What should I avoid while using Orencia®?

Do not receive a "live" vaccine while using Orencia®, and for at least 3 months after your treatment ends. Tell your doctor at once if you develop signs of infection.